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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
18.18
Human Site:
S893
Identified Species:
30.77
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
S893
A
Q
K
K
R
V
E
S
I
Q
C
F
Q
N
T
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
S893
A
Q
K
K
R
V
E
S
I
Q
C
F
Q
N
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
S990
A
Q
K
K
R
V
E
S
I
Q
C
F
Q
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
S887
A
Q
K
K
R
V
E
S
I
Q
R
F
Q
N
T
Rat
Rattus norvegicus
NP_001099948
974
110023
S858
A
Q
K
K
R
V
E
S
I
Q
C
F
Q
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
S797
G
G
V
G
L
N
L
S
A
A
S
R
V
F
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
A883
T
Q
K
K
R
T
E
A
I
Q
S
F
Q
R
P
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
A828
I
Q
R
A
R
A
K
A
I
E
D
F
Q
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
I950
P
V
K
N
R
Q
D
I
V
N
E
F
N
D
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
A972
S
R
I
A
R
T
A
A
I
R
E
F
S
S
N
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
N712
K
A
S
G
A
G
I
N
L
A
V
A
S
R
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
N794
K
A
S
G
T
G
I
N
L
T
A
A
S
R
V
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
L703
L
K
A
G
G
V
A
L
N
L
C
E
A
S
Q
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
V1110
S
Q
K
A
R
A
A
V
L
T
E
F
Q
S
T
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
6.6
N.A.
60
33.3
N.A.
20
N.A.
N.A.
20
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
6.6
N.A.
66.6
73.3
N.A.
40
N.A.
N.A.
53.3
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
0
N.A.
N.A.
0
13.3
40
P-Site Similarity:
13.3
N.A.
N.A.
13.3
26.6
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
15
8
22
8
15
22
22
8
15
8
15
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
36
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
8
0
0
15
0
% D
% Glu:
0
0
0
0
0
0
43
0
0
8
22
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
72
0
8
0
% F
% Gly:
8
8
0
29
8
15
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
15
8
58
0
0
0
0
0
0
% I
% Lys:
15
8
58
43
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
8
0
8
8
22
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
15
8
8
0
0
8
36
8
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
58
0
0
0
8
0
0
0
43
0
0
58
0
8
% Q
% Arg:
0
8
8
0
72
0
0
0
0
8
8
8
0
22
8
% R
% Ser:
15
0
15
0
0
0
0
43
0
0
15
0
22
22
8
% S
% Thr:
8
0
0
0
8
15
0
0
0
15
0
0
0
0
43
% T
% Val:
0
8
8
0
0
43
0
8
8
0
8
0
8
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _